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KMID : 0363819950290040526
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Korean Journal of Nuclear Medicine
1995 Volume.29 No. 4 p.526 ~ p.532
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The Clinical Role of 99mTc-(V)-DMSA Imaging in Patients with Head and Neck Cancer
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배선근
이재태/박준식/박인규/현동우/이영학/김정균/안병철/최지용
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Abstract
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Introduction :
@EN 99mTc-(V)-DMSA is a tumor seeking agent that has been used to image medullary carcinoma of thyroid, soft tissue sarcoma and lung cancer. This study was designed to assess the clinical role of 99mTc-(V)-DMSA in the diagnosis of head and neck
cancers.
We has evaluated the diagnostic efficacy of planar and SPECT imaging using 99mTc-(V)-DMSA.
@ES Patients and Method :
@EN Sixty-eight patients with head and neck mass were included in this study. All subjects were diagnosed by biopsy or surgery. Planar and SPECT images were obtained at 2 or 3 hour after intravenous injection of 740 MBq(20 mCi) 99mTc-(V)-DMSA.
Seventeen
patients also underwent SPECT imaging using dual head camera.
@ES Result :
@EN The diagnostic sensitivity of 99mTc-(V)-DMSA planar and SPECT imaging was 65% and 90%, and specificity was 80% and 66%, respectively. The sensitivity of planar imaging in squamous cell carcinoma was similar to overall sensitivity. Six
metastatic
lesion were first diagnosed by scintigraphy. But benign lesions such as Kikuchi syndrome, tuberculous lymphadenitis also revealed increased uptake.
@ES Conclusion :
@EN 99mTc(V)-DMSA imaging seems to be a promising method in the evaruation of patients with head and neck mass. We recommend SPECT imaging to delineate anatomic localization of the lesion.
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KEYWORD
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